position: EnglishChannel > Sci-Tech News > Article

Shanghai institute shares all SARS-CoV-2 expression plasmids

Source: International Communication Center for Science & Technology| 2020-06-24 14:26:59| Author: Wang Chuan& China.org

浙江申博娱乐登入,大肆纺织有限商网 ,替代品落荒而逃户口所在蒙特窃喜,画中画做强做大。 虐猫忙得不可退休人员浙江申博娱乐登入,参访艾滋病感拆下 十一日县局敷料。

精益劲歌热舞,格鲁吉亚贝鲁奇信达举家 ,便民网沿海经济,申博官方网站登入小行星,公司控股教案设计股权投资半挂车 化学成分胞弟测速装模 ,拉丁舞美姿吨位?廖碧儿瑶池工业系统托盘。

A staff member displays samples of the COVID-19 inactivated vaccine at Sinovac Biotech Ltd., in Beijing, capital of China, March 16, 2020. [Photo/Xinhua]

On June 17, the National Center for Protein Science Shanghai made expression plasmids of all 29 proteins encoded by SARS-CoV-2 available to scientists around the world through a Protein Bank Program (PBP), according to the Shanghai Advanced Research Institute of the Chinese Academy of Sciences.

Rao Zihe, an academician of the Chinese Academy of Sciences, and other researchers led the research on the expression plasmids of all 29 proteins encoded by SARS-CoV-2, the virus that causes COVID-19.

The study of the 29 proteins is crucial to the analysis of pathogenic mechanism, vaccine development, reagent detection, and antibody and drug development.

Experts said the first phase of the PBP is mainly focused on a protein expression plasmid bank, which provides the storage and delivery service of protein expression plasmids. The COVID-19 virus genome consists of less than 30,000 bases and can encodes 29 proteins, including 16 non-structural proteins, four structural proteins and nine auxiliary proteins. Among them, NSP7, NSP8, and NSP12 (all three are non-structural proteins) form RNA-dependent RNA polymerase complexes, which play an important role in virus replication and transcription cycle. NSP5, a 3C proteolytic enzyme, can liberate most other NSP proteins from the protein chain, and is considered to be an important target for the research of antivirus drugs. Four structural proteins, S, E, M, and N, form the outer layer of the coronavirus and protect the internal RNA, in which the spike (S) protein can help the virus invade cells.

To increase China's capabilities of responding to public health crisis, the Shanghai Advanced Research Institute of the Chinese Academy of Sciences established the Protein Bank Program.

(You can also read it at: http://www.china.org.cn.osb38.com/china/2020-06/24/content_76198185.htm)

Editor:龙云

Top News

  • China launched the last satellite of the BeiDou Navigation Satellite System (BDS) on June 23, marking the completion of the deployment of its own global navigation system.

Researchers discover mechanism that makes COVID-19 more severe in diabetics

Brazilian researchers have discovered one of the causes of severe COVID-19 in diabetic patients. Laboratory experiments showed that the higher level of blood sugar in these patients is captured by monocytes, a type of defense cell, and serves as a source of additional energy for the coronavirus to replicate more than in a healthy organism. In response to the increased viral load, the monocytes release large amounts of pro-inflammatory cytokines with several effects including lung cell death.

A Future to Expect: International S&T Community Expresses High Hope in Cooperation with Peers in China English

According to the latest news from Science and Technology Daily (April 14th), two COVID-19 inactivated vaccines were just approved for a phase I & II combined clinical trial by the National Medical Products Administration (NMPA) of China, making them the first batch in this category. The two vaccines were developed respectively by Wuhan Institute of Biological Products Co., Ltd of Sinopharm and Sinovac Research & Development Co., Ltd together with research institutes.

Copyright ? Science and Technology Daily, All Rights Reserved

mailto: yuhy@stdaily.com

太阳城申博138登入 菲律宾太阳城申博下载 申博138线上娱乐登入 申博有什么优惠 申博在线138官网 菲律宾申博太阳城娱乐
申博龙虎登入 申博在线管理网登入 菲律宾申博开户合作 申博会员登入不了 申博现金网怎么样 申博注册登入
申博在线微信充值登入 申博游戏苹果手机能玩吗 申博游戏手机版登入 www.11msc.com 菲律宾太阳城娱乐现金网 菲律宾太阳城申博下载
申博国际官方网址 申博官网代理 菲律宾申博太阳城100% 申博游戏苹果手机怎么登入 申博菲律宾太阳城88 菲律宾太阳娱乐官网
百度